Application of nanoparticle mediated N-arylation of amines for the synthesis of pharmaceutical entities using vit-E analogues as amphiphiles in water
Author:
Affiliation:
1. Medicinal and Process Chemistry Division
2. CSIR-Central Drug Research Institute
3. Lucknow
4. India
Abstract
The first CuI-nanoparticle catalyzed inter and intramolecular N-arylation of amines using vitamin E analogues as amphiphiles was developed in water and is extended to azoles, substituted indoles, a bioactive natural product and intermediates of pharmaceutical entities.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C4RA15267K
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