Application of nanoparticle mediated N-arylation of amines for the synthesis of pharmaceutical entities using vit-E analogues as amphiphiles in water

Author:

Kumar Atul1234,Bishnoi Ajay Kumar1234

Affiliation:

1. Medicinal and Process Chemistry Division

2. CSIR-Central Drug Research Institute

3. Lucknow

4. India

Abstract

The first CuI-nanoparticle catalyzed inter and intramolecular N-arylation of amines using vitamin E analogues as amphiphiles was developed in water and is extended to azoles, substituted indoles, a bioactive natural product and intermediates of pharmaceutical entities.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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