A 2,7-dichlorofluorescein derivative to monitor microcalcifications

Author:

Tholen Patrik1,Brown Connor N.2,Keil Claudia1ORCID,Bayir Ali3,Zeng Hui-Hui4,Haase Hajo1ORCID,Thompson Richard B.4,Lengyel Imre2ORCID,Yücesan Gündoğ1ORCID

Affiliation:

1. Institute for Food Chemistry and Toxicology, Germany, Technische Universität Berlin, Gustav-Meyer-Allee 25, 13355 Berlin, Germany

2. Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast BT9 7BL, UK

3. The Department of Chemistry, Yıldız Technical University, 34220, Esenler, Istanbul, Turkey

4. Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA

Abstract

Herein, we report the crystal structure of 2,7-dichlorofluorescein methyl ester (DCF-ME) and its fluorescence response to hydroxyapatite binding.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Industrial and Manufacturing Engineering,Process Chemistry and Technology,Energy Engineering and Power Technology,Biomedical Engineering,Chemical Engineering (miscellaneous),Chemistry (miscellaneous)

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