Exploring the binding pattern between pepsin and deferasirox using detailed experimental and computer simulation methods
Author:
Affiliation:
1. School of Chemical Engineering
2. Sichuan University
3. Chengdu
4. China
5. R&D Center of China Tobacco Yunnan Industrial Co., Ltd.
6. Kunming
Abstract
Investigation on the binding properties of deferasirox to pepsin.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA07993E
Reference35 articles.
1. Oral chelators deferasirox and deferiprone for transfusional iron overload in thalassemia major: new data, new questions
2. Iron chelation with deferasirox in adult and pediatric patients with thalassemia major: efficacy and safety during 5 years' follow-up
3. Investigation on the interaction behavior between bisphenol A and pepsin by spectral and docking studies
4. Mechanism of pepsin catalysis: General base catalysis by the active-site carboxylate ion
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