The gene expression profiling of hepatocellular carcinoma by a network analysis approach shows a dominance of intrinsically disordered proteins (IDPs) between hub nodes-Reference-Cited by-同舟云学术

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The gene expression profiling of hepatocellular carcinoma by a network analysis approach shows a dominance of intrinsically disordered proteins (IDPs) between hub nodes

Published:2015 Issue:11 Volume:11 Page:2933-2945
ISSN:1742-206X
Container-title:Molecular BioSystems
language:en
Short-container-title:Mol. BioSyst.

Author:

Singh Sakshi¹²³⁴⁵,Colonna Giovanni⁶⁷⁸⁵⁹,Di Bernardo Giovanni¹⁰⁴⁵⁹,Bergantino Francesca¹¹¹²⁵⁹,Cammarota Marcella¹⁰⁴⁵⁹,Castello Giuseppe¹¹¹²⁵⁹,Costantini Susan¹¹¹²⁵⁹

Affiliation:

1. Dottorato in Biologia Computazionale

2. Dipartimento di Biochimica

3. Biofisica e Patologia generale

4. Seconda Università degli Studi di Napoli

5. Napoli

6. Servizio di Informatica Medica

7. Azienda Ospedaliera Universitaria

8. Seconda Università di Napoli

9. Italy

10. Dipartimento di Medicina Sperimentale

11. CROM

12. Istituto Nazionale Tumori “Fondazione G. Pascale” – IRCCS

Abstract

The results evidence a strong presence of intrinsically disordered proteins in key roles as hubs in HCC sub-networks.

Publisher

Royal Society of Chemistry (RSC)

Subject

Molecular Biology,Biotechnology

Link

http://pubs.rsc.org/en/content/articlepdf/2015/MB/C5MB00434A

Reference104 articles.

1. Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

2. Liver cancer: Descriptive epidemiology and risk factors other than HBV and HCV infection

3. Overweight, obesity and risk of liver cancer: a meta-analysis of cohort studies

4. Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis

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1. System-Wide Pollution of Biomedical Data: Consequence of the Search for Hub Genes of Hepatocellular Carcinoma Without Spatiotemporal Consideration;Molecular Diagnosis & Therapy;2021-01

2. Identification of Hub Genes and Analysis of Prognostic Values in Hepatocellular Carcinoma by Bioinformatics Analysis;The American Journal of the Medical Sciences;2020-04

3. Evaluating the associations between human circadian rhythms and dysregulated genes in liver cancer cells;Oncology Letters;2017-09-29

4. Relevance of Intrinsic Disorder in Protein Structure and Function;SpringerBriefs in Biochemistry and Molecular Biology;2016

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