Cyclopalladated organosilane–tethered thiosemicarbazones: novel strategies for improving antiplasmodial activity-Reference-Cited by-同舟云学术

Cyclopalladated organosilane–tethered thiosemicarbazones: novel strategies for improving antiplasmodial activity

Published:2016 Issue:13 Volume:45 Page:5514-5520
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Adams Muneebah¹²³⁴,Barnard Linley¹²³⁴,de Kock Carmen⁵⁶²⁷⁸,Smith Peter J.⁵⁶²⁷⁸,Wiesner Lubbe⁵⁶²⁷⁸,Chibale Kelly¹²³⁴⁹,Smith Gregory S.¹²³⁴

Affiliation:

1. Department of Chemistry

2. University of Cape Town

3. Rondebosch 7701

4. South Africa

5. Division of Pharmacology

6. Department of Medicine

7. K45

8. OMB

9. Institute of Infectious Disease and Molecular Medicine

Abstract

Ferrocenyl- and aryl-derived cyclopalladated organosilane thiosemicarbazone complexes were synthesised via C–H bond activation and evaluated for antiplasmodial activity.

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/DT/C5DT04918K

Reference47 articles.

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2. World Health Organisation , Global Plan for Artemisinin Resistance Containment (GPARC), 2011

3. Antimalarial drug discovery – the path towards eradication

4. Exploring the Versatility of Cycloplatinated Thiosemicarbazones as Antitumor and Antiparasitic Agents

5. Synthesis and antimalarial activity of semicarbazone and thiosemicarbazone derivatives

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