Advances in ultrahigh-throughput screening for directed enzyme evolution-Reference-Cited by-同舟云学术

Advances in ultrahigh-throughput screening for directed enzyme evolution

Published:2020 Issue:1 Volume:49 Page:233-262
ISSN:0306-0012
Container-title:Chemical Society Reviews
language:en
Short-container-title:Chem. Soc. Rev.

Author:

Markel Ulrich¹²³⁴^ORCID,Essani Khalil D.¹²³⁴,Besirlioglu Volkan¹²³⁴,Schiffels Johannes¹²³⁴^ORCID,Streit Wolfgang R.⁵⁶⁷⁴^ORCID,Schwaneberg Ulrich¹²³⁴⁸^ORCID

Affiliation:

1. Institute of Biotechnology

2. RWTH Aachen University

3. 52074 Aachen

4. Germany

5. Department of Microbiology and Biotechnology

6. Universität Hamburg

7. 22609 Hamburg

8. DWI – Leibniz Institute for Interactive Materials

Abstract

This review summarizes how ultrahigh-throughput screening methods employ cells and biomimetic compartments to access the vast, unexplored diversity of biocatalysts with novel functions derived from directed evolution and metagenomics libraries.

Funder

Bundesministerium für Bildung und Forschung

H2020 Marie Skłodowska-Curie Actions

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/CS/C8CS00981C

Reference309 articles.

1. Innovation by Evolution: Bringing New Chemistry to Life (Nobel Lecture)