C-Linked 8-aryl guanine nucleobase adducts: biological outcomes and utility as fluorescent probes
Author:
Affiliation:
1. Department of Chemistry & Toxicology
2. University of Guelph
3. Guelph
4. Canada N1G 2W1
5. Department of Chemistry & Biochemistry
6. University of Lethbridge
7. Lethbridge
8. Canada T1K 3M4
Abstract
We summarize the utility and biological outcomes resulting from direct attachment of aryl residues to the 8-site of the guanine nucleobase to afford mutagenic lesions and fluorescent probes in G-quadruplex structures.
Funder
Natural Sciences and Engineering Research Council of Canada
Canada Research Chairs
Canada Foundation for Innovation
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/SC/C6SC00053C
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