Exploration of novel cationic amino acid-enriched short peptides: design, SPPS, biological evaluation and in silico study

Author:

Chandole Prashant K.1,Pawar Tushar Janardan2ORCID,Olivares-Romero José Luis2ORCID,Tivari Sunil R.1,Garcia Lara Bianney3,Patel Harun4,Ahmad Iqrar4,Delgado-Alvarado Enrique5ORCID,Kokate Siddhant V.6,Jadeja Yashwantsinh1ORCID

Affiliation:

1. Department of Chemistry, Marwadi University, Rajkot-360003, Gujarat, India

2. Red de Estudios Moleculares Avanzados, Instituto de Ecología, A.C. Carretera Antigua a Coatepec 351, Xalapa, 91073, Veracruz, Mexico

3. Departamento de Química, Universidad de Guanajuato, Noria Alta S/N, Guanajuato-36050, Guanajuato, Mexico

4. Department of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur District Dhule-425405, Maharashtra, India

5. Micro and Nanotechnology Research Center, Universidad Veracruzana, Blvd. Av. Ruiz Cortines No. 455 Fracc. Costa Verde, Boca del Río 94294, Mexico

6. Department of Chemistry, S. S. C. College, Junnar, Pune-410502, Maharashtra, India

Abstract

Antimicrobial resistance (AMR) represents a critical challenge worldwide, necessitating the pursuit of novel approaches to counteract bacterial and fungal pathogens.

Funder

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

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