Tuning the properties of tris(hydroxypyridinone) ligands: efficient 68Ga chelators for PET imaging-Reference-Cited by-同舟云学术

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Tuning the properties of tris(hydroxypyridinone) ligands: efficient 68Ga chelators for PET imaging

Published:2019 Issue:13 Volume:48 Page:4299-4313
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Imberti Cinzia¹²³⁴⁵^ORCID,Chen Yu-Lin¹⁶⁷⁸⁹,Foley Calum A.¹²³⁴⁵,Ma Michelle T.¹²³⁴⁵^ORCID,Paterson Brett M.¹²³⁴⁵^ORCID,Wang Yifu¹²³⁴⁵,Young Jennifer D.¹²³⁴⁵,Hider Robert C.¹⁶⁷⁸⁹,Blower Philip J.¹²³⁴⁵^ORCID

Affiliation:

1. King's College London

2. School of Biomedical Engineering and Imaging Sciences

3. St Thomas’ Hospital

4. London SE1 7EH

5. UK

6. School of Biomedical Sciences

7. Institute of Pharmaceutical Science

8. London

9. SE1 9NH UK

Abstract

The outstanding efficiency of the tris(hydroxypyridonone) ligand THP^Me for radiolabelling PET radiotracers with ⁶⁸Ga is surpassed by THP^H.

Funder

Cancer Research UK

Engineering and Physical Sciences Research Council

Medical Research Council

King’s College London

Wellcome Trust

National Institute for Health Research

State Government of Victoria

Department of Health & Social Care

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/DT/C8DT04454F

Reference52 articles.

1. Continued rapid growth in68Ga applications: update 2013 to June 2014

2. Prospective of 68Ga-Radiopharmaceutical Development

3. Technetium and Gallium Derived Radiopharmaceuticals: Comparing and Contrasting the Chemistry of Two Important Radiometals for the Molecular Imaging Era

4. Positron Emitting [68Ga]Ga-Based Imaging Agents: Chemistry and Diversity

5. PET imaging with a [68Ga]gallium-labelled PSMA ligand for the diagnosis of prostate cancer: biodistribution in humans and first evaluation of tumour lesions

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