Picrotoxane sesquiterpenoids: chemistry, chemo- and bio-syntheses and biological activities

Author:

Shi Qiang-Qiang1ORCID,Tang Jiang-Jiang1ORCID,Gao Jin-Ming1ORCID

Affiliation:

1. Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, 22 Xinong Road, Yangling 712100, Shaanxi, People's Republic of China

Abstract

This review summarizes a total of 132 picrotoxane sesquiterpenoids to date, focusing on their structural diversity, chemo- and bio-syntheses, and biological activities.

Funder

National Natural Science Foundation of China

Northwest A and F University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference260 articles.

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3. E.Gössinger , in Progress in the Chemistry of Organic Natural Products , Springer , Vienna , 2010 , vol. 93 , pp. 71–210

4. Evolution of synthetic strategies and design for synthesis of (−)-picrotoxinin

5. Advances on the Total Synthesis of Sesquiterpenoid Alkaloid Dendrobine

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