Mononuclear Co(<scp>ii</scp>) polypyridyl complexes: synthesis, molecular structure, DNA binding/cleavage, radical scavenging, docking studies and anticancer activities-Reference-Cited by-同舟云学术

Mononuclear Co(ii) polypyridyl complexes: synthesis, molecular structure, DNA binding/cleavage, radical scavenging, docking studies and anticancer activities

Published:2022 Issue:18 Volume:51 Page:7084-7099
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Karumban Kalai Selvan¹^ORCID,Muley Arabinda¹^ORCID,Raut Rajnikant²^ORCID,Gupta Parth²^ORCID,Giri Bishnubasu¹,Kumbhakar Sadananda¹,Misra Ashish²,Maji Somnath¹^ORCID

Affiliation:

1. Department of Chemistry, Indian Institute of Technology, Kandi, Sangareddy, Hyderabad 502284, Telangana, India

2. Department of Biotechnology, Indian Institute of Technology, Kandi, Sangareddy, Hyderabad 502284, Telangana, India

Abstract

A series of mononuclear Co(ii) complexes were synthesized and structurally identified as potent metal-based anti-cancer drugs with excellent DNA cleavage activity and significant cytotoxicity in A549 and MDA-MB-231 cells.

Funder

Science and Engineering Research Board

Council of Scientific and Industrial Research, India

Ministry of Education, India

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/DT/D1DT04144D

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1. Models for prevention and treatment of cancer: Problems vs promises