Recent developments in the synthesis and applications of chiral ferrocene ligands and organocatalysts in asymmetric catalysis

Author:

Cunningham Laura12345ORCID,Benson Annette23456ORCID,Guiry Patrick J.12345ORCID

Affiliation:

1. Synthesis and Solid State Pharmaceutical Centre

2. Centre for Synthesis and Chemical Biology

3. School of Chemistry

4. University College Dublin

5. Dublin 4

6. Ireland

Abstract

This review highlights recent advances in the synthesis and application of ferrocene-containing chiral ligands and organocatalysts in asymmetric catalysis.

Funder

Science Foundation Ireland

Irish Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference113 articles.

1. O. B. Sutcliffe and M. R.Bryce , Planar Chiral 2-Ferrocenyloxazolines and 1,1′-Bis(Oxazolinyl)Ferrocenes - Syntheses and Applications in Asymmetric Catalysis , Tetrahedron: Asymmetry , 2003 , 2297–2325

2. A Novel Easily Accessible Chiral Ferrocenyldiphosphine for Highly Enantioselective Hydrogenation, Allylic Alkylation, and Hydroboration Reactions

3. Highly Efficient Asymmetric Synthesis of Sitagliptin

4. Chiral π-Complexes of Heterocycles with Transition Metals:  A Versatile New Family of Nucleophilic Catalysts

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