Understanding the structural requirements of cyclic sulfone hydroxyethylamines as hBACE1 inhibitors against Aβ plaques in Alzheimer's disease: a predictive QSAR approach-Reference-Cited by-同舟云学术

Understanding the structural requirements of cyclic sulfone hydroxyethylamines as hBACE1 inhibitors against Aβ plaques in Alzheimer's disease: a predictive QSAR approach

Published:2016 Issue:34 Volume:6 Page:28171-28186
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Ambure Pravin¹²³⁴⁵,Roy Kunal¹²³⁴⁵

Affiliation:

1. Drug Theoretics and Cheminformatics Laboratory

2. Department of Pharmaceutical Technology

3. Jadavpur University

4. Kolkata 700032

5. India

Abstract

Beta (β)-site amyloid precursor protein cleaving enzyme 1 (BACE1) is one of the most important targets in Alzheimer's disease (AD), which is responsible for production and accumulation of beta amyloid (Aβ).

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA04104C

Reference32 articles.

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