A ligand-free strategy for the copper-catalysed direct alkynylation of trifluoromethyl ketones
Author:
Affiliation:
1. School of Chemistry and Chemical Engineering
2. Key Laboratory for Green Processing of Chemical Engineering of Xinjiang Bingtuan
3. Shihezi University
4. Shihezi
5. China
Abstract
A superbase-induced copper-catalyzed direct alkynylation method for trifluoromethyl ketones was developed without any additional ligand under mild conditions.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C4RA14322A
Reference44 articles.
1. Grignard type reaction via C–H bond activation in water
2. Phosphine-Triggered Complete Chemo-Switch: From Efficient Aldehyde−Alkyne−Amine Coupling to Efficient Aldehyde−Alkyne Coupling in Water
3. The Development of Catalytic Nucleophilic Additions of Terminal Alkynes in Water
4. Trifluoromethyl ketones: properties, preparation, and application
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