Hydroxypyridinones with enhanced iron chelating properties. Synthesis, characterization and in vivo tests of 5-hydroxy-2-(hydroxymethyl)pyridine-4(1H)-one-Reference-Cited by-同舟云学术

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Hydroxypyridinones with enhanced iron chelating properties. Synthesis, characterization and in vivo tests of 5-hydroxy-2-(hydroxymethyl)pyridine-4(1H)-one

Published:2016 Issue:15 Volume:45 Page:6517-6528
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Lachowicz J. I.¹²³⁴,Nurchi V. M.¹²³⁴,Crisponi G.¹²³⁴,Jaraquemada-Pelaez M. G.¹²³⁴,Arca M.¹²³⁴,Pintus A.¹²³⁴,Santos M. A.⁵⁶⁷⁸⁹,Quintanova C.⁵⁶⁷⁸⁹,Gano L.¹⁰¹¹⁷¹²⁹,Szewczuk Z.¹³¹⁴¹⁵¹⁶,Zoroddu M. A.¹⁷¹⁸¹⁹⁴,Peana M.¹⁷¹⁸¹⁹⁴,Domínguez-Martín A.²⁰²¹²²²³²⁴,Choquesillo-Lazarte D.²⁵²⁶²⁷²⁴²⁸

Affiliation:

1. Department of Chemical and Geological Science

2. University of Cagliari

3. 09042 Monserrato-Cagliari

4. Italy

5. Centro Quimica Estrutural

6. Instituto Superior Tecnico

7. Universidade de Lisboa

8. 1049-001 Lisboa

9. Portugal

10. Campus Tecnológico e Nuclear

11. Instituto Superior Técnico

12. 2695-066 Bobadela LRS

13. Faculty of Chemistry

14. University of Wroclaw

15. 50-383 Wroclaw

16. Poland

17. Dipartimento di Chimica e Farmacia

18. Università di Sassari

19. 07100 Sassari

20. Department of Inorganic Chemistry

21. Faculty of Pharmacy

22. Campus Cartuja

23. University of Granada

24. Granada

25. Laboratorio de Estudios Cristalográficos

26. IACT

27. CSIC-Universidad de Granada

28. Spain

Abstract

an tautomeric changes positively influence coordinating ability?

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/DT/C6DT00129G

Reference52 articles.

1. Synthesis, Physicochemical Characterization, and Biological Evaluation of 2-(1‘-Hydroxyalkyl)-3-hydroxypyridin-4-ones: Novel Iron Chelators with Enhanced pFe3+ Values

2. Hydroxypyridinone complexes with aluminium. In vitro/vivo studies and perspectives

3. Hydroxypyridinones as “privileged” chelating structures for the design of medicinal drugs

4. Ferric ion sequestering agents. 13. Synthesis, structures, and thermodynamics of complexation of cobalt(III) and iron(III) tris complexes of several chelating hydroxypyridinones

5. Synthesis, physicochemical properties, and biological evaluation of N-substituted 2-alkyl-3-hydroxy-4(1H)-pyridinones: orally active iron chelators with clinical potential

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2. Insights Into the Synthetic Strategies, Biological Activity, and Structure- Activity Relationship of Pyridine and Analogs: A Review;Letters in Organic Chemistry;2023-09-07

3. NMR and EPR study of the interaction of tris(3-hydroxy-4-pyridinonato) Ga(III) complexes with liposomes that mimic plant membranes;Biophysical Chemistry;2023-07

4. A Comparative DFT Study on the Antioxidant Activity of Some Novel 3‐Hydroxypyridine‐4‐One Derivatives;Chemistry & Biodiversity;2022-01-27

5. Recent advances in therapeutical applications of the versatile hydroxypyridinone chelators;Journal of Inclusion Phenomena and Macrocyclic Chemistry;2022-01-16

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