Development of highly active anti-Pneumocystisbisbenzamidines: insight into the influence of selected substituents on thein vitroactivity-Reference-Cited by-同舟云学术

Development of highly active anti-Pneumocystisbisbenzamidines: insight into the influence of selected substituents on thein vitroactivity

Author:

Maciejewska D.¹²³⁴⁵^ORCID,Żabiński J.¹²³⁴⁵,Rezler M.¹²³⁴⁵,Kaźmierczak P.¹²³⁴⁵,Collins M. S.⁶⁷⁸⁹¹⁰,Ficker L.⁶⁷⁸⁹¹⁰,Cushion M. T.⁶⁷⁸⁹¹⁰

Affiliation:

1. Department of Organic Chemistry

2. Faculty of Pharmacy

3. Medical University of Warsaw

4. 02-097 Warsaw

5. Poland

6. Division of Infectious Diseases

7. Department of Internal Medicine

8. University of Cincinnati College of Medicine

9. Cincinnati

10. USA

Abstract

A detailed SAR study with 21 pentamidine analogues was undertaken. Four new leading structures were identified.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

Reference37 articles.

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