A reaction-based near-infrared fluorescent probe that can visualize endogenous selenocysteine in vivo in tumor-bearing mice

Author:

Zhang Ling12345ORCID,Kai Xiaoning678910,Zhang Yiran678910,Zheng Youguang678910,Xue Yunsheng678910,Yin Xiaoxing678910ORCID,Zhao Jing12345ORCID

Affiliation:

1. State Key Laboratory of Coordination Chemistry

2. Institute of Chemistry and BioMedical Sciences

3. School of Chemistry and Chemical Engineering

4. Nanjing University

5. Nanjing 210093

6. Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy

7. Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy

8. School of Pharmacy

9. Xuzhou Medical University

10. Xuzhou 221002

Abstract

Endogenously generated selenocysteine in tumor-bearing mice were selectively detected by our reaction-based NIR probe for the first time.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Jiangsu University

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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