Engineering dithiobenzoic acid lactone-decorated Si-rhodamine as a highly selective near-infrared HOCl fluorescent probe for imaging drug-induced acute nephrotoxicity

Author:

Wang Jinping12345,Cheng Dan12345,Zhu Longmin12345,Wang Peng12345,Liu Hong-Wen12345ORCID,Chen Mei12345ORCID,Yuan Lin12345ORCID,Zhang Xiao-Bing12345ORCID

Affiliation:

1. State Key Laboratory of Chemo/Biosensing and Chemometrics

2. College of Chemistry and Chemical Engineering

3. College of Materials Science and Engineering

4. Hunan University

5. Changsha

Abstract

A NIR fluorescent probe based on Si-rhodamine dithiobenzoic acid lactone was used to selectively visualize HOCl during GEN-induced nephrotoxicity for the first time.

Funder

National Natural Science Foundation of China

Hunan Provincial Science and Technology Department

China Postdoctoral Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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