Two hydrazone copper(ii) complexes: synthesis, crystal structure, cytotoxicity, and action mechanism
Author:
Affiliation:
1. State Key Laboratory Cultivation Base for the Chemistry and Molecular Engineering of Medicinal Resources
2. School of Chemistry and Pharmacy
3. Guangxi Normal University
4. Guilin 541004
5. P. R. China
Abstract
Two hydrazone copper(ii) complexes 1 and 2 exhibited significantly cytotoxicity. MGC80-3 cells are more sensitive to complexes versus normal liver cells. And the mechanism of cell cytotoxicity against the MGC80-3 cancer cell was studied.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA03478K
Reference39 articles.
1. Developing new metal-based therapeutics: challenges and opportunities
2. Mechanistic insight into the cellular uptake and processing of cisplatin 30 years after its approval by FDA
3. Direct Cellular Responses to Platinum-Induced DNA Damage
4. Current Status of Platinum-Based Antitumor Drugs
5. Biochemical Modulation of Cisplatin Mechanisms of Action: Enhancement of Antitumor Activity and Circumvention of Drug Resistance
Cited by 21 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Spectral Characterization and Antimicrobial Activity of Chenodeoxycholic Acid Complexes with Zn(II), Mg(II), and Ca(II) Ions;Crystals;2023-07-27
2. Complexes of the Antibiotic Drug Oxolinic Acid with Fe(III), Zn(II), Ca(II), and Mg(II) Ions: Preparation, Characterization, and In Vitro Evaluation of Biological Activity;Crystals;2023-06-25
3. Chrysin Encapsulated Copper Nanoparticles with Low Dose of Gamma Radiation Elicit Tumor Cell Death Through p38 MAPK/NF-κB Pathways;Biological Trace Element Research;2023-03-11
4. Copper coordination compounds based on bis-quinolylhydrazone of 2,6-diacetylpyridine: Synthesis, structure and cytotoxic activity;Polyhedron;2023-03
5. Tridentate acylhydrazone copper(II) complexes with heterocyclic bases as coligands. Synthesis, spectroscopic studies, crystal structure and cytotoxicity assays;Polyhedron;2022-02
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3