Fast and sensitive fluorescent probe for ratiometric detection of hydrogen sulfide in mitochondria-Reference-Cited by-同舟云学术

Fast and sensitive fluorescent probe for ratiometric detection of hydrogen sulfide in mitochondria

Published:2019 Issue:2 Volume:11 Page:232-235
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Jiang Na¹²³⁴^ORCID,Wang Bin¹²³⁴,Liu Tao⁵⁶⁷⁴,Liu Qingyu¹²³⁴,Wei Qin¹²³⁴,Xing Yujing¹²³⁴,Zheng Gengxiu¹²³⁴

Affiliation:

1. School of Chemistry and Chemical Engineering

2. University of Jinan

3. Jinan

4. China

5. Department of Chemical Engineering

6. Chengde Petroleum College

7. Chengde

Abstract

A hemicyanine-based fluorescent dye, Mito-BT, was developed to ratiometrically detect H₂S. This dye was of high selectivity, photostability and sensitivity with a rapid response time of 10 seconds. In addition, Mito-BT was localized in mitochondria, making it a promising probe for detecting H₂S in cells.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Shandong Province

University of Jinan

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/AY/C8AY02586J

Reference29 articles.

1. Hydrogen sulfide (H2S) metabolism in mitochondria and its regulatory role in energy production