Unexpected enrichment of DNA aptamers for Zn<sup>2+</sup> ions from an insulin selection-Reference-Cited by-同舟云学术

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Unexpected enrichment of DNA aptamers for Zn²⁺ ions from an insulin selection

Published:2024 Issue:49 Volume:60 Page:6280-6283
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Liu Yibo¹²,Wang Xiaoqin¹,Liu Juewen¹²^ORCID

Affiliation:

1. Department of Chemistry, Waterloo Institute for Nanotechnology, University of Waterloo, Waterloo, Ontario, N2L 3G1, Canada

2. Centre for Eye and Vision Research (CEVR), 17W Hong Kong Science Park, Hong Kong, China

Abstract

With an effort to select for DNA aptamers that can bind to insulin, Zn2+-binding aptamers were obtained instead. The Zn-1 aptamer showed 450-fold selectivity towards Zn2+ compared to Cd2+.

Funder

Natural Sciences and Engineering Research Council of Canada

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CC/D4CC01546K

Reference38 articles.

1. Fluorescent detection of zinc in biological systems: recent development on the design of chemosensors and biosensors

2. High-Efficiency in Vitro and in Vivo Detection of Zn2+ by Dye-Assembled Upconversion Nanoparticles

3. Small-Molecule Fluorescent Sensors for Investigating Zinc Metalloneurochemistry

4. Fluorescent chemosensors for Zn2+

5. Photoluminescence imaging of Zn2+in living systems

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