Anti-cancer effects of wedelolactone: interactions with copper and subcellular localization-Reference-Cited by-同舟云学术

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Anti-cancer effects of wedelolactone: interactions with copper and subcellular localization

Published:2018 Issue:10 Volume:10 Page:1524-1531
ISSN:1756-5901
Container-title:Metallomics
language:en
Short-container-title:Metallomics

Author:

Kučírková Tereza¹²³⁴⁵,Stiborek Marek⁶³⁷⁵,Dúcka Monika¹²³⁴⁵,Navrátilová Jarmila¹²³⁴⁵,Bogdanović Pristov Jelena⁸⁹¹⁰¹¹¹²,Popović-Bijelić Ana¹³¹⁴¹⁰¹¹¹²,Vojvodić Snežana⁸⁹¹⁰¹¹¹²,Preisler Jan⁶³⁷⁵¹⁵,Kanický Viktor⁶³⁷⁵¹⁵,Šmarda Jan¹²³⁴⁵,Spasojević Ivan⁸⁹¹⁰¹¹¹²^ORCID,Beneš Petr¹²³⁴⁵

Affiliation:

1. Department of Experimental Biology

2. Faculty of Science

3. Masaryk University

4. 62500 Brno

5. Czech Republic

6. Department of Chemistry

7. 625 00 Brno

8. Department of Life Sciences

9. Institute for Multidisciplinary Research

10. University of Belgrade

11. Belgrade

12. Serbia

13. EPR Laboratory

14. Faculty of Physical Chemistry

15. CEITEC–Central European Institute of Technology

Abstract

Wedelactone forms a 2 : 1 coordination complex with Cu²⁺ in cancer cells to exert cytotoxic effects.

Funder

Grantová Agentura České Republiky

Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja

Masarykova Univerzita

Ministerstvo Školství, Mládeže a Tělovýchovy

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2018/MT/C8MT00191J

Reference39 articles.

1. Plant Coumestans: Recent Advances and Future Perspectives in Cancer Therapy

2. Inhibition of topoisomerase IIα: Novel function of wedelolactone

3. Redox state alters anti-cancer effects of wedelolactone

4. Wedelolactone Acts as Proteasome Inhibitor in Breast Cancer Cells

5. Electrochemical Activity of Wedelolactone and Probing its Interaction with DNA Using Voltammetry at a Carbon Electrode

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1. Two‐Phase Electrosynthesis of Dihydroxycoumestans: Discovery of a New Scaffold for Topoisomerase I Poison;Chemistry – A European Journal;2024-06-20

2. Molecular mechanism of wedelolactone inhibits high glucose-induced human retinal vascular endothelial cells injury through regulating miR-190 expression;Medicine;2024-05-24

3. UPLC-QTOF-MS-based lipidomic study of wedelolactone in acute colitis mice induced by dextran sulfate sodium;Heliyon;2023-09

4. Catecholase-catalyzed synthesis of wedelolactone, a natural coumestan and its analogs;Organic & Biomolecular Chemistry;2023

5. Biological activities of polypyridyl-type ligands: implications for bioinorganic chemistry and light-activated metal complexes;Current Opinion in Chemical Biology;2021-04

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