Solid lipid nanoparticles as an effective sodium aescinate delivery system: formulation and anti-inflammatory activity-Reference-Cited by-同舟云学术

Solid lipid nanoparticles as an effective sodium aescinate delivery system: formulation and anti-inflammatory activity

Published:2022 Issue:11 Volume:12 Page:6583-6591
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Wang Jinyue¹,Wang Hongyue²,Xu Hongjia¹,Li Jinghan³,Zhang Xu²,Zhang Xiangrong¹²^ORCID

Affiliation:

1. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China

2. School of Function Food and Wine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China

3. Department of Pharmaceutics, College of Pharmacy, University of Minnesota-Twin Cities, 308 SE Harvard St, Minneapolis, 55455, Minnesota, USA

Abstract

Solid lipid nanoparticles (SLNs) to encapsulate sodium aescinate (SA) were prepared by a double emulsion (DE) technique. SLNs were optimized by orthogonal and Box–Behnken designs. SLNs – SA presented a higher anti-inflammatory activity than free SA.

Funder

Department of Science and Technology of Liaoning Province

Department of Education of Liaoning Province

Shenyang Pharmaceutical University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D1RA07638H

Reference33 articles.

1. CARMA3/NF-κB signaling contributes to tumorigenesis of hepatocellular carcinoma and is inhibited by sodium aescinate