Mechanistic insights into the in vitro metal-promoted oxidation of (di)azine hydroxamic acids: evidence of HNO release and N,O-di(di)azinoyl hydroxylamine intermediate
Author:
Affiliation:
1. CNRS, Laboratoire de Chimie de Coordination
2. LCC
3. UPR 8241
4. F-31077 Toulouse
5. France
6. Laboratório de Bioinorgânica
7. Universidade Federal do Ceará
8. Departamento de Química Orgânica e Inorgânica
9. Fortaleza
10. Brazil
Abstract
HNO is released through a one-electron oxidation of the hydroxamic acid along with the N,O-di(di)azinoylhydroxylamine intermediate.
Funder
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Fundação Cearense de Apoio ao Desenvolvimento Científico e Tecnológico
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,General Chemistry,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2020/NJ/D0NJ00753F
Reference25 articles.
1. Nitroxyl (azanone) trapping by metalloporphyrins
2. Nitroxyl and its anion in aqueous solutions: Spin states, protic equilibria, and reactivities toward oxygen and nitric oxide
3. Nitroxyl (HNO): the Cinderella of the nitric oxide story
4. NO − Activates Soluble Guanylate Cyclase and K v Channels to Vasodilate Resistance Arteries
5. Nitroxyl Anion Donor, Angeli’s Salt, Does Not Develop Tolerance in Rat Isolated Aortae
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