A deoxygenation-switch-based red-emitting fluorogenic light-up probe for the detection of highly toxic free bilirubin in human blood serum

Author:

Ahmmed Ejaj1,Mondal Asit1,Chandra Saha Nimai2ORCID,Dhara Koushik3ORCID,Chattopadhyay Pabitra1ORCID

Affiliation:

1. Department of Chemistry, The University of Burdwan, Burdwan-713104, West Bengal, India

2. Vice Chancellor's Research Group, The University of Burdwan, Burdwan, West Bengal, 713104, India

3. Department of Chemistry, Sambhu Nath College, Labpur, Birbhum 731303, West Bengal, India

Abstract

A new benzorhodol-based fluorogenic probe with a ‘turn on’ mechanism, having a biofriendly excitation wavelength (580 nm), was used to analyze biologically toxic free bilirubin in aqueous buffer medium.

Funder

Department of Science and Technology, Government of West Bengal

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Reference41 articles.

1. J. R.Chowdhury , A. W.Wolkoff , I. M.Arias , C. R.Scriver , A. L.Beaudet , W. S.Sly and D.Valle , The Metabolic Basis of Inherited Diseases , McGraw-Hill , New York , part 8, 1989 , vol. 1 , pp. 1367–1408

2. K. E.Barrett , Bilirubin Formation and Excretion by the Liver , Gastrointestinal Physiology , McGraw-Hill , New York , 2014 , 2nd edn sec-iv, ch. 13

3. Usefulness of the bilirubin/albumin ratio for predicting bilirubin-induced neurotoxicity in premature infants

4. Synthesis of the multi-walled carbon nanotubes-COOH/graphene/gold nanoparticles nanocomposite for simple determination of Bilirubin in human blood serum

5. Via zinc(II) protoporphyrin to the synthesis of poly(ZnPP-MAA-EGDMA) for the imprinting and selective binding of bilirubin

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