A mannose-conjugated multi-layered polymeric nanocarrier system for controlled and targeted release on alveolar macrophages

Author:

Praphakar Rajendran Amarnath12345,Shakila Harshavardhan67458,Azger Dusthackeer Vijayan N.910118,Munusamy Murugan A.12131415,Kumar Suresh16171819,Rajan Mariappan12345ORCID

Affiliation:

1. Biomaterials in Medicinal Chemistry Laboratory

2. Department of Natural Products Chemistry

3. School of Chemistry

4. Madurai Kamaraj University

5. Madurai-625021

6. Department of Molecular Microbiology

7. School of Biotechnology

8. India

9. Department of Bacteriology

10. National Institute for Research in Tuberculosis

11. Chennai

12. Department of Botany and Microbiology

13. King Saud University

14. Riyadh 11451

15. Saudi Arabia

16. Department of Medical Microbiology and Parasitology

17. Universiti Putra Malaysia

18. 43400 Serdang

19. Malaysia

Abstract

To improve the performance of drug delivery systems in macrophages, targeted ligand-conjugated polymeric carriers have been realized to be vital for targeted, sustainable and controlled drug release with remarkable biocompatibility and bioavailability.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

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