l-Proline mediated synthesis of quinoxalines; evaluation of cytotoxic and antimicrobial activity
Author:
Affiliation:
1. Medicinal Chemistry and Pharmacology
2. CSIR-Indian Institute of Chemical Technology
3. Hyderabad 500 007, India
Abstract
A simple, greener and highly efficient method for the synthesis of functionalized quinoxalines has been developed employing l-proline as a catalyst in water. The newly synthesized quinoxaline–sulphonamide conjugates exhibited significant cytotoxic and antimicrobial activities.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/RA/C4RA08615E
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