An IMDAF approach to annellated 1,4:5,8-diepoxynaphthalenes and their metathesis reaction leading to novel scaffolds displaying an antiproliferative activity toward cancer cells-Reference-Cited by-同舟云学术

An IMDAF approach to annellated 1,4:5,8-diepoxynaphthalenes and their metathesis reaction leading to novel scaffolds displaying an antiproliferative activity toward cancer cells

Published:2021 Issue:41 Volume:45 Page:19497-19505
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Kvyatkovskaya Elizaveta A.¹^ORCID,Borisova Kseniya K.¹^ORCID,Epifanova Polina P.¹,Senin Aleksey A.¹^ORCID,Khrustalev Victor N.¹²^ORCID,Grigoriev Mikhail S.³,Bunev Alexander S.⁴^ORCID,Gasanov Rovshan E.⁴,Polyanskii Kirill B.¹,Zubkov Fedor I.¹^ORCID

Affiliation:

1. Organic Chemistry Department, Faculty of Science, Peoples’ Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St., Moscow 117198, Russian Federation

2. N. D. Zelinsky Institute of Organic Chemistry of RAS, 47 Leninsky Prospect, 119991, Moscow, Russian Federation

3. A. N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Leninsky pr. 31, bld. 4, Moscow, 119071, Russian Federation

4. Medicinal Chemistry Center, Togliatti State University, 14 Belorusskaya St., Togliatti, 445020, Russian Federation

Abstract

A 3,5a-epoxyfuro[2,3,4-de]isoquinoline scaffold, the product of ROCM of 1,4:5,8-diepoxynaphthalenes, is a promising antiproliferative agent toward breast and prostate human cancer cell lines.

Funder

Ministry of Education and Science of the Russian Federation

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NJ/D1NJ03991A

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