From oximes to tertiary alcohols in water, at room temperature and under air: a hybrid one-pot tandem assembly of enzymatic deoximation and RLi/RMgX reagents-Reference-Cited by-同舟云学术

From oximes to tertiary alcohols in water, at room temperature and under air: a hybrid one-pot tandem assembly of enzymatic deoximation and RLi/RMgX reagents

Published:2023 Issue:21 Volume:21 Page:4414-4421
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Arnodo Davide¹²^ORCID,Ramos-Martín Marina¹^ORCID,Cicco Luciana¹³^ORCID,Capriati Vito³^ORCID,Ríos-Lombardía Nicolás¹⁴^ORCID,González-Sabín Javier⁴^ORCID,Presa Soto Alejandro¹^ORCID,García-Álvarez Joaquín¹^ORCID

Affiliation:

1. Laboratorio de Química Sintética Sostenible (QuimSinSos), Departamento de Química Orgánica e Inorgánica, (IUQOEM), Centro de Innovación en Química Avanzada (ORFEO-CINQA), Facultad de Química, Universidad de Oviedo, E33071 Oviedo, Spain

2. Dipartimento di Chimica-Università degli Studi di Torino, Via P. Giuria 7, 10125 Torino, Italy

3. Dipartimento di Farmacia-Scienze del Farmaco, Università di Bari “Aldo Moro”, Consorzio C.I.N.M.P.I.S., Via E. Orabona 4, I-70125 Bari, Italy

4. EntreChem SL, Vivero Ciencias de la Salud. Santo Domingo de Guzmán, Oviedo, 33011, Spain

Abstract

The design of a hybrid one-pot tandem protocol through the combination of biodeoximations (promoted by laccase from Trametes versicolor) and s-block polar organometallics (RLi/RMgX) in aqueous media, at room temperature and under air is reported.

Funder

Consiglio Nazionale delle Ricerche

Gobierno del Principado de Asturias

Ministerio de Ciencia e Innovación

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB00285C

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