A solvent controlled regioselective synthesis of 2- and 4-substituted α-carbolines under palladium catalysis-Reference-Cited by-同舟云学术

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A solvent controlled regioselective synthesis of 2- and 4-substituted α-carbolines under palladium catalysis

Published:2024 Issue:58 Volume:60 Page:7427-7430
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Chatterjee Sarat¹,Khatun Rousunara²³,Ali Mahammad²^ORCID,Chowdhury Chinmay¹^ORCID

Affiliation:

1. Organic and Medicinal Chemistry Division, CSIR-Indian Institute of Chemical Biology, Kolkata-700032, India

2. Department of Chemistry, Jadavpur University, 188, Raja S. C. Mullick Road, Kolkata, India

3. Aliah University, 11-A/27, Action Area II, Newtown, Kolkata, India

Abstract

A solvent controlled method for the chemodivergent synthesis of α-carbolines 1via palladium catalyzed [3+3]-annulations of tosyliminoindolines 6 with α, β-unsaturated aldehydes 7 is described along with reaction mechanism and photo-physical study.

Funder

CSIR - Indian Institute of Chemical Biology

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CC/D4CC00668B

Reference44 articles.

1. Biomimetic Synthesis of Grossularines-1

2. Structure of mescengricin, a novel neuronal cell protecting substance produced by Streptomyces griseoflavus

3. Grossularine-1 and grossularine-2, cytotoxic α-carbolines from the tunicate: Dendrodoa grossularia

4. Total synthesis of grossularines-1 and -2

5. Implitapide, a Microsomal Triglyceride Transfer Protein Inhibitor, Reduces Progression of Atherosclerosis in Apolipoprotein E Knockout Mice Fed a Western-Type Diet: Involvement of the Inhibition of Postprandial Triglyceride Elevation

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