Direct observation of peptide hydrogel self-assembly-Reference-Cited by-同舟云学术

Direct observation of peptide hydrogel self-assembly

Published:2022 Issue:34 Volume:13 Page:10020-10028
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Adams Zoë C.¹^ORCID,Olson Erika J.¹,Lopez-Silva Tania L.²^ORCID,Lian Zhengwen¹,Kim Audrey Y.¹,Holcomb Matthew¹^ORCID,Zimmermann Jörg¹^ORCID,Adhikary Ramkrishna¹^ORCID,Dawson Philip E.¹^ORCID

Affiliation:

1. Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California, 92037, USA

2. Chemical Biology Laboratory, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA

Abstract

To facilitate the characterization of phase-transitioning molecules, site-specific non-perturbative infrared probes are leveraged for continuous observation of the self-assembly of fibrils in a peptide hydrogel following stopped-flow initiation.

Funder

National Science Foundation

National Institute of General Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SC/D1SC06562A

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1. Distinct β-Sheet Structure in Protein Aggregates Determined by ATR–FTIR Spectroscopy

2. Amyloid fibrils