Visible light mediated PVA-tyramine hydrogels for covalent incorporation and tailorable release of functional growth factors

Author:

Atienza-Roca Pau1234,Kieser David C.1234ORCID,Cui Xiaolin1234ORCID,Bathish Boushra1234,Ramaswamy Yogambha5678,Hooper Gary J.1234ORCID,Clarkson Andrew N.91011124ORCID,Rnjak-Kovacina Jelena1314158ORCID,Martens Penny J.1314158ORCID,Wise Lyn M.16114ORCID,Woodfield Tim B. F.1234ORCID,Lim Khoon S.1234ORCID

Affiliation:

1. Department of Orthopaedic Surgery

2. University of Otago Christchurch

3. Christchurch 8011

4. New Zealand

5. School of Biomedical Engineering

6. University of Sydney

7. Sydney 2006

8. Australia

9. Department of Anatomy

10. Brain Health Research Centre and Brain Research New Zealand

11. University of Otago

12. Dunedin 9054

13. Graduate School of Biomedical Engineering

14. UNSW Sydney

15. Sydney 2052

16. Department of Pharmacology and Toxicology

Abstract

PVA-Tyr hydrogel facilitated covalent incorporation can control release of pristine growth factors while retaining their native bioactivity.

Funder

Canterbury Medical Research Foundation

University of Otago

Ministry of Business, Innovation and Employment

Royal Society of New Zealand

National Heart Foundation of Australia

Health Research Council of New Zealand

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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