High-purity butoxydibutylborane catalysts enable the low-exothermic polymerization of PMMA bone cement with enhanced biocompatibility and osseointegration

Author:

Wan Zhuo1,Gao Yike2,Wang Yingbo3,Zhang Xianghao3,Gao Xiyin4,Zhou Tuanfeng3,Zhang Zhishan5,Li Zijian5,Lin Yunfei6,Wang Bing6,Chen Kun1,Wang Yang3,Duan Chenggang3,Yuan Zuoying17ORCID

Affiliation:

1. Department of Mechanics and Engineering Science, College of Engineering, Peking University, Beijing 100871, P. R. China

2. Laboratory of Tissue Regeneration and Immunology and Department of Periodontics, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, School of Stomatology, Capital Medical University, Beijing 100050, P. R. China

3. Department of Oral and Maxillofacial Surgery, The First Clinical Division, The Third Clinical Division, and The Fifth Clinical Division, Peking University School of Stomatology, 100020 Beijing, P. R. China

4. Key Laboratory of Science and Technology on High-tech Polymer Materials, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China

5. Department of Orthopedics, Peking University Third Hospital, Beijing 100191, P. R. China

6. Department of Orthopaedic Surgery, Peking University First Hospital, Beijing 100034, P. R. China

7. Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing 100871, P. R. China

Abstract

Polymethyl methacrylate (PMMA) biomaterials, catalyzed by high-purity butoxydibutylborane (BODBB) and characterized by excellent biocompatibility and osseointegration, demonstrate substantial potential for future clinical applications.

Funder

Natural Science Foundation of Beijing Municipality

China Postdoctoral Science Foundation

Publisher

Royal Society of Chemistry (RSC)

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