Aptamer-functionalized nanopipettes: a promising approach for viral fragment detection via ion current rectification

Author:

Denuga Shekemi1ORCID,Duleba Dominik1ORCID,Dutta Pallavi1,Macori Guerrino23ORCID,Corrigan Damion K.4ORCID,Fanning Séamus25ORCID,Johnson Robert P.12ORCID

Affiliation:

1. School of Chemistry, University College Dublin, Belfield, Dublin 4, Ireland

2. UCD-Centre for Food Safety, University College Dublin, Belfield, Dublin 4, Ireland

3. School of Biology and Environmental Science, University College Dublin, Belfield, Dublin 4, Ireland

4. Centre for Advanced Measurement Science and Health Translation, Department of Pure and Applied Chemistry, University of Strathclyde, G1 1XL, UK

5. School of Public Health, Physiotherapy & Sports Science, University College Dublin, Belfield, Dublin 4, Ireland

Abstract

Ion current rectifying nanopipettes successfully differentiate viral fragments from SARS-COV-2 positive nasopharyngeal samples, demonstrating the sensing platform's potential as a sensitive and selective technology for infectious disease detection.

Funder

National University of Ireland

Irish Research Council

Science Foundation Ireland

Publisher

Royal Society of Chemistry (RSC)

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