Three birds one stone: an enzyme-activatable theragnostic agent for fluorescence diagnosis, photodynamic and inhibitor therapies-Reference-Cited by-同舟云学术

Three birds one stone: an enzyme-activatable theragnostic agent for fluorescence diagnosis, photodynamic and inhibitor therapies

Published:2023 Issue:31 Volume:59 Page:4676-4679
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Yue Xiuxiu¹,Wang Benhua¹^ORCID,Lan Minhuan¹^ORCID,Fan Jiangli²^ORCID,Song Xiangzhi¹,Foley James W.³

Affiliation:

1. College of Chemistry & Chemical Engineering, Central South University, Changsha, 410083, Hunan Province, China

2. State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian, 116024, Liaoning Province, China

3. Rowland Institute at Harvard, Harvard University, Cambridge, 02142, Massachusetts, USA

Abstract

By integrating the inhibitor of KIAA1363 enzyme, AX11890, into a red-absorbing dye, a tumor microenvironmental-responsive photosensitizer, NBS-L-AX, was developed for selective fluorescence imaging and activatable PDT therapy for breast cancers.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC00214D

Reference16 articles.

1. Recent progresses in small-molecule enzymatic fluorescent probes for cancer imaging

2. A Third Zinc-binding Domain of Human Poly(ADP-ribose) Polymerase-1 Coordinates DNA-dependent Enzyme Activation

3. Synthesis and structure–activity relationship of (1-halo-2-naphthyl) carbamate-based inhibitors of KIAA1363 (NCEH1/AADACL1)

4. An Enzyme that Regulates Ether Lipid Signaling Pathways in Cancer Annotated by Multidimensional Profiling

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