Fenton-like nanoparticles capable of H<sub>2</sub>O<sub>2</sub> self-supply and glutathione consumption for chemodynamic and chemotherapy of cancer-Reference-Cited by-同舟云学术

Fenton-like nanoparticles capable of H₂O₂ self-supply and glutathione consumption for chemodynamic and chemotherapy of cancer

Published:2024 Issue: Volume: Page:
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

He Yongju¹^ORCID,Tian Xiangjie¹,Zhang Meiru¹,Xu Hui²,Gong Xiyu³,Yang Binbin³,Zhou Fangfang³^ORCID

Affiliation:

1. School of Materials Science and Engineering, Central South University, Changsha 410083, Hunan, China

2. Institute of Super-Microstructure and Ultrafast Process in Advanced Materials, School of Physics and Electronics, Central South University, Changsha 410083, Hunan, China

3. Department of Neurology, The Second Xiangya Hospital of Central South University, Changsha 410011, Hunan, China

Abstract

A multifunctional nanosystem featuring a synergy of “H2O2 supplementation–GSH depletion–Fenton-like activity” was successfully developed to enhance CDT and concomitantly combine it with chemotherapy for tumor treatment.

Funder

Natural Science Foundation of Hunan Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/BM/D4BM00930D

Reference40 articles.

1. Recent advances of cancer chemodynamic therapy based on Fenton/Fenton-like chemistry

2. Manipulating Intratumoral Fenton Chemistry for Enhanced Chemodynamic and Chemodynamic‐Synergized Multimodal Therapy

3. Biomedicine Meets Fenton Chemistry

4. Glutathione-triggered release of SO₂ gas to augment oxidative stress for enhanced chemodynamic and sonodynamic therapy

5. Self-sufficient copper peroxide loaded pKa-tunable nanoparticles for lysosome-mediated chemodynamic therapy