Synthetic- and DFT modelling studies on regioselective modified Mannich reactions of hydroxy-KYNA derivatives-Reference-Cited by-同舟云学术

Synthetic- and DFT modelling studies on regioselective modified Mannich reactions of hydroxy-KYNA derivatives

Published:2021 Issue:1 Volume:11 Page:543-554
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Lőrinczi Bálint¹²³⁴⁵^ORCID,Csámpai Antal⁶⁷⁸⁵,Fülöp Ferenc¹²³⁴⁵,Szatmári István¹²³⁴⁵^ORCID

Affiliation:

1. Institute of Pharmaceutical Chemistry and Research Group for Stereochemistry

2. Hungarian Academy of Sciences

3. University of Szeged

4. H-6720 Szeged

5. Hungary

6. Department of Inorganic Chemistry

7. Eötvös Loránd University (ELTE)

8. H-1117 Budapest

Abstract

New side of KYNA in modified Mannich reaction – systematic investigation of the reactivity of hydroxylated derivatives rationalised with comparative DFT calculations.

Funder

Nemzeti Kutatási Fejlesztési és Innovációs Hivatal

Emberi Erőforrások Minisztériuma

Nemzeti Kutatási, Fejlesztési és Innovaciós Alap

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D0RA08325A

Reference33 articles.

1. The Janus-face kynurenic acid

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4. Mitochondria, metabolic disturbances, oxidative stress and the kynurenine system, with focus on neurodegenerative disorders

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