Integrated analysis of serum and intact muscle metabonomics identify metabolic profiles of cancer cachexia in a dynamic mouse model-Reference-Cited by-同舟云学术

Integrated analysis of serum and intact muscle metabonomics identify metabolic profiles of cancer cachexia in a dynamic mouse model

Published:2015 Issue:112 Volume:5 Page:92438-92448
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

QuanJun Yang¹²³⁴,GenJin Yang⁵⁶⁷⁴,LiLi Wan¹²³⁴,Yan Huo¹²³⁴,YongLong Han¹²³⁴,Jin Lu¹²³⁴,Jie Li¹²³⁴,JinLu Huang¹²³⁴,Cheng Guo¹²³⁴

Affiliation:

1. Department of Pharmacy

2. Shanghai Jiao Tong University Affiliated Sixth People’s Hospital

3. Shanghai 200233

4. P. R. China

5. School of Pharmacy

6. Second Military Medical University

7. Shanghai 200433

Abstract

An integrated analysis of 13 metabolites from the intact muscle gastrocnemius and 43 metabolites from the serum reveals five distinguishable metabolic features of cancer cachexia.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA19004E

Reference43 articles.

1. Definition and classification of cancer cachexia: an international consensus

2. Why cachexia kills: examining the causality of poor outcomes in wasting conditions

3. Cancer Cachexia and Fat–Muscle Physiology

4. Critical weight loss is a major prognostic indicator for disease-specific survival in patients with head and neck cancer receiving radiotherapy

5. Muscle Wasting in Cancer Cachexia: Clinical Implications, Diagnosis, and Emerging Treatment Strategies

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