Acid-responsive endosomolytic polymeric nanoparticles with amplification of intracellular oxidative stress for prodrug delivery and activation-Reference-Cited by-同舟云学术

Acid-responsive endosomolytic polymeric nanoparticles with amplification of intracellular oxidative stress for prodrug delivery and activation

Published:2021 Issue: Volume: Page:
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Lu Nannan¹²³⁴⁵,Xi Longchang⁶⁷⁴⁸⁹,Zha Zengshi⁶⁷⁴⁸⁹,Wang Yuheng⁶⁷⁴⁸⁹,Han Xinghua¹²³⁴⁵,Ge Zhishen⁶⁷⁴⁸⁹^ORCID

Affiliation:

1. Department of Oncology

2. The First Affiliated Hospital of USTC

3. Division of Life Science and Medicine

4. University of Science and Technology of China

5. Hefei 230001

6. CAS Key Laboratory of Soft Matter Chemistry

7. Department of Polymer Science and Engineering

8. Hefei 230026

9. China

Abstract

A pH-responsive endosomolytic polymeric micelle was engineered to deliver oxidation-activable prodrugs into the cytoplasm of cancer cells for modulation of intracellular oxidative stress and prodrug activation after endosomal escape.

Funder

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Natural Science Foundation of Anhui Province

Anhui Provincial Key Research and Development Plan

University of Science and Technology of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D1BM00159K

Reference54 articles.

1. Weekly Paclitaxel in the Adjuvant Treatment of Breast Cancer

2. Topotecan – A Novel Topoisomerase I Inhibitor: Pharmacology and Clinical Experience

3. The resurgence of platinum-based cancer chemotherapy

4. Cardiovascular Complications of Cancer Therapy

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Recent Advances in Stimuli-Responsive Self-Immolative Polymers for Drug Delivery and Molecular Imaging;Chemistry of Materials;2024-04-18

2. Anticancer nano-prodrugs with drug release triggered by intracellular dissolution and hydrogen peroxide response;Chemical Communications;2024

3. Stimulus‐Responsive Nano‐Prodrug Strategies for Cancer Therapy: A Focus on Camptothecin Delivery;Small Methods;2023-12-12

4. Therapy of mitochondria-targeted hybrid nanozymes for reactive oxygen species-induced diseases;Applied Materials Today;2023-08

5. Cascade-amplified self-immolative polymeric prodrug for cancer therapy by disrupting redox homeostasis;Journal of Controlled Release;2023-06