Unprecedented access to functionalized pyrrolo[2,1-a]isoquinolines from the domino reaction of isoquinolinium ylides and electrophilic benzannulated heterocycles
Author:
Affiliation:
1. Chemical Sciences and Technology Division
2. CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST)
3. Thiruvananthapuram 695019
4. India
5. Academy of Scientific and Innovative Research (AcSIR)
Abstract
The reaction between electrophilic benzannulated heterocycles and isoquinolinium methylides results in a domino dipolar cycloaddition-ring opening transformation, generating functionalized pyrrolo[2,1-a]isoquinolines and S–S-bridged bis-pyrrolo[2,1-a]isoquinolines.
Funder
Council of Scientific and Industrial Research
University Grants Commission
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB00005E
Reference66 articles.
1. Electrophilicity: the “dark-side” of indole chemistry
2. An abnormal Barton–Zard reaction leading to the pyrrolo[2,3-b]indole ring system
3. One-step syntheses of the pyrrolo[3,4-b]indole and pyrrolo[2,3-b]indole ring systems from 3-nitroindoles
4. Diels-Alder reactions of N-tosyl-3-nitroindole and dienamides: synthesis of intermediates ofAspidospermine alkaloids
5. Activation of the Dienophilicity of Indoles in Normal Electron Demand [4 + 2] Cycloadditions under High Pressure
Cited by 19 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Cascade Synthesis of Pyrrolo[1,2-a]quinolines and Pyrrolo[2,1-a]isoquinolines via Formal [3 + 2]-Cycloaddition of Push–Pull Nitro Heterocycles with Carbonyl-Stabilized Quinolinium/Isoquinolinium Ylides;The Journal of Organic Chemistry;2024-06-25
2. Base-Mediated Cascade Lactonization/1,3-Dipolar Cycloaddition Pathway for the One-Pot Assembly of Coumarin-Functionalized Pyrrolo[2,1-a]isoquinolines;The Journal of Organic Chemistry;2024-06-05
3. Investigations on Superbase Mediated Reactivity of N‐Tosylhydrazones with Aza‐ortho‐Quinone Methide Precursors;European Journal of Organic Chemistry;2024-04-17
4. Leveraging Pyrazolium Ylide Reactivity to Access Indolizine and 1,2‐Dihydropyrimidine Derivatives;Chemistry – A European Journal;2024-04-05
5. Tandem Reactions of Electrophilic Indoles toward Indolizines and Their Subsequent Transformations through Pd(II)-Mediated C–H Functionalization to Access Polyring-Fused N-Heterocycles;ACS Omega;2024-03-30
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3