Cancer-associated fibroblast-targeted nanodrugs reshape colorectal tumor microenvironments to suppress tumor proliferation, metastasis and improve drug penetration-Reference-Cited by-同舟云学术

Cancer-associated fibroblast-targeted nanodrugs reshape colorectal tumor microenvironments to suppress tumor proliferation, metastasis and improve drug penetration

Published:2023 Issue:9 Volume:11 Page:1871-1880
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Shen Wenqi¹²,Yao Ping-an³,Li Wenjing²^ORCID,Gu Changji¹,Gao Tian²^ORCID,Cao Yi²^ORCID,Wang Zheng²^ORCID,Pei Renjun²,Xing Chungen¹

Affiliation:

1. Department of General Surgery, Second Affiliated Hospital of Soochow University, Suzhou, 215004, P. R. China

2. CAS Key Laboratory for Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, 215123, P. R. China

3. Department of Gastrointestinal Surgery, Shanghai East Hospital (East Hospital Affiliated to Tongji University), 150 Jimo Road, Shanghai, 200120, China

Abstract

Cancer-associated fibroblasts (CAFs) produce a critical tumor-promoting effect by cellular crosstalk with cancer cells and remodel the extracellular matrix (ECM) to form a protective physical barrier.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Jiangsu Science and Technology Department

Jiangsu Commission of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2023/TB/D2TB02253B

Reference44 articles.