Modulating the folding and binding of peptides using a stimuli-responsive molecular tweezer-Reference-Cited by-同舟云学术

Modulating the folding and binding of peptides using a stimuli-responsive molecular tweezer

Published:2023 Issue:35 Volume:14 Page:9600-9607
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Ko Sooho¹,Kim Joo-Young²,Park Jung Yeon³,Jung You-jin¹^ORCID,Choi Min-Jae⁴,Jin Kyeong Sik⁵,Kim Yongju³^ORCID,Lim Yong-beom¹^ORCID,Jeong Woo-jin²⁶^ORCID

Affiliation:

1. Department of Materials Science and Engineering, Yonsei University, Seoul 03722, Republic of Korea

2. Department of Biological Sciences and Bioengineering, Inha University, Incheon, 22212, Republic of Korea

3. KU-KIST Graduate School of Converging Science and Technology, Department of Integrative Energy Engineering, Korea University, Seoul 02841, Republic of Korea

4. Department of Chemical & Biochemical Engineering, Dongguk University, Seoul, 06420, Republic of Korea

5. Pohang Accelerator Laboratory, Pohang University of Science and Technology, Pohang 790-784, Republic of Korea

6. Department of Biological Engineering, Inha University, Incheon, 22212, Republic of Korea

Abstract

This study presents the development of a β-hairpin (tryptophan zipper, Trpzip)-based molecular tweezer (MT) that can control the folding and binding of α-helical peptides.

Funder

National Research Foundation of Korea

Ministry of Science and ICT, South Korea

Ministry of Trade, Industry and Energy

Ministry of SMEs and Startups

Inha University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D3SC03758D