Fragmentation study of tryptophan-derived metabolites induced by electrospray ionization mass spectrometry for highly sensitive analysis-Reference-Cited by-同舟云学术

Fragmentation study of tryptophan-derived metabolites induced by electrospray ionization mass spectrometry for highly sensitive analysis

Published:2021 Issue:7 Volume:146 Page:2292-2300
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Asakawa Daiki¹²³^ORCID,Mizuno Hajime⁴⁵⁶³^ORCID,Sugiyama Eiji⁴⁵⁶³^ORCID,Todoroki Kenichiro⁴⁵⁶³^ORCID

Affiliation:

1. National Institute of Advanced Industrial Science and Technology

2. Tsukuba

3. Japan

4. School of Pharmaceutical Sciences

5. University of Shizuoka

6. Shizuoka 422-8526

Abstract

ESI of tryptophan-derived metabolites produced an intense signal of fragment ion with a spiro[cyclopropane-indolium] backbone. The use of corresponding fragment ions for the precursor of MRM transitions could improve the detection limit.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/AN/D0AN02069A

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