The acidic hydrolysis of N-acetylneuraminic 4,5-oxazoline allows a direct functionalization of the C5 position of Neu5Ac2en (DANA)-Reference-Cited by-同舟云学术

The acidic hydrolysis of N-acetylneuraminic 4,5-oxazoline allows a direct functionalization of the C5 position of Neu5Ac2en (DANA)

Author:

Rota Paola¹²³⁴^ORCID,La Rocca Paolo⁵²³⁴,Cirillo Federica⁶⁷³⁴,Piccoli Marco⁶⁷³⁴,Allevi Pietro¹²³⁴,Anastasia Luigi⁶⁷³⁴⁸

Affiliation:

1. Department of Biomedical, Surgical and Dental Sciences

2. University of Milan

3. Milan

4. Italy

5. Department of Biomedical Sciences for Health

6. Laboratory of Stem Cells for Tissue Engineering

7. IRCCS Policlinico San Donato, San Donato Milanese

8. University of Vita-Salute San Raffaele

Abstract

The Neu5Ac 4,5-oxazoline ring-opening allows the direct generation of a free C5-amino group key to synthesize antiviral drugs.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

Reference24 articles.

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1. Molecular Rearrangements;Organic Reaction Mechanisms Series;2024-03-15