Personalized tissue-engineered veins – long term safety, functionality and cellular transcriptome analysis in large animals-Reference-Cited by-同舟云学术

Personalized tissue-engineered veins – long term safety, functionality and cellular transcriptome analysis in large animals

Published:2023 Issue:11 Volume:11 Page:3860-3877
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Österberg Klas¹,Bogestål Yalda²,Jenndahl Lachmi³^ORCID,Gustafsson-Hedberg Tobias³,Synnergren Jane⁴⁵,Holmgren Gustav⁴,Bom Eva²,Petronis Sarunas²^ORCID,Krona Annika⁶,Eriksson Jonna S.⁷,Rosendahl Jennifer²^ORCID,Crisostomo Veronica⁸⁹¹⁰^ORCID,Sanchez-Margallo Francisco M.⁸⁹¹⁰,Baez-Diaz Claudia⁸⁹¹⁰,Strehl Raimund³,Håkansson Joakim²¹¹^ORCID

Affiliation:

1. Sahlgrenska Academy, Institution of Medicine, Wallenberg Laboratory, Department of Molecular and Clinical Medicine, Blå Stråket 5 B, 41345 Gothenburg, Sweden

2. RISE Research Institutes of Sweden, Methodology, Textile and Medical Device, Brinellgatan 4, 50462 Borås, Sweden

3. VERIGRAFT AB, Arvid Wallgrensbacke 20, 41346, Göteborg, Sweden

4. Systems Biology Research Center, School of Bioscience, University of Skövde, 54128 Skövde, Sweden

5. Gothenburg University, Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, 41345 Gothenburg, Sweden

6. RISE Research Institutes of Sweden, Agriculture and Food, Box 5401, 40229 Gothenburg, Sweden

7. TATAA Biocenter AB, Gothenburg, Sweden

8. Jesús Usón Minimally Invasive Surgery Centre, Cáceres 10004, Spain

9. CIBER de Enfermedades Cardiovasculares, CIBER CV, Madrid 28029, Spain

10. RICORS-TERAV Network, ISCIII, Madrid 28029, Spain

11. Gothenburg University, Department of Laboratory Medicine, Institute of Biomedicine, Gothenburg, Sweden

Abstract

Donor veins were decellularized and reconditioned with the recipient's blood to produce autologous personalized tissue engineered veins. After 1 year in vivo, all grafts were patent and morphologically and genetically very similar with native veins.

Funder

VINNOVA

Västra Götalandsregionen

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/BM/D2BM02011D

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