Design, clinical applications and post-surgical assessment of bioresorbable 3D-printed craniofacial composite implants

Author:

Targońska Sara12,Dobrzyńska-Mizera Monika3,Di Lorenzo Maria Laura4ORCID,Knitter Monika3,Longo Alessandra45,Dobrzyński Maciej6ORCID,Rutkowska Monika7,Barnaś Szczepan7,Czapiga Bogdan7,Stagraczyński Maciej7,Mikulski Michał8,Muzalewska Małgorzata9,Wyleżoł Marek9,Rewak-Soroczyńska Justyna1,Nowak Nicole1,Andrzejewski Jacek3,Reeks John1,Wiglusz Rafal J.101ORCID

Affiliation:

1. Institute of Low Temperature and Structure Research, PAS, Okolna 2, PL-50-422 Wroclaw, Poland

2. Department of Molecular Sciences, Swedish University of Agricultural Sciences, Box 7015, 75007 Uppsala, Sweden

3. Institute of Materials Technology, Polymer Division, Poznan University of Technology, Piotrowo 3, 61-138 Poznan, Poland

4. National Research Council (CNR), Institute of Polymers, Composites and Biomaterials (IPCB), Via Campi Flegrei, 34, 80078 Pozzuoli (NA), Italy

5. National Research Council (CNR), Institute of Polymers, Composites and Biomaterials (IPCB), Via Paolo Gaifami 18, 95126, Catania, CT, Italy

6. Department of Pediatric Dentistry and Preclinical Dentistry, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland

7. 4th Military Teaching Hospital, R. Weigla, PL-50-981 Wroclaw, Poland

8. NZOZ Artdent, Piekarska 11-13, 62-800 Kalisz, Poland

9. Department of Fundamentals of Machinery Design, Faculty of Mechanical Engineering Silesian University of Technology, Gliwice, Poland

10. Department of Organic Chemistry, Bioorganic Chemistry and Biotechnology, Silesian University of Technology, Krzywoustego 4, 44-100 Gliwice, Poland

Abstract

This paper describes in detail the design, fabrication, clinical trial evaluation and post clinical application analysis of 3D-printed bone implants made from the nHAp@PLDLLA [nanohydroxyapatite; poly(l-lactide-co-d,l-lactide)] biomaterial.

Funder

Narodowe Centrum Nauki

Politechnika Poznańska

Narodowe Centrum Badań i Rozwoju

Publisher

Royal Society of Chemistry (RSC)

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