Palladium-catalyzed three-component carbonylative synthesis of 2-(trifluoromethyl)quinazolin-4(3H)-ones from trifluoroacetimidoyl chlorides and amines-Reference-Cited by-同舟云学术

Palladium-catalyzed three-component carbonylative synthesis of 2-(trifluoromethyl)quinazolin-4(3H)-ones from trifluoroacetimidoyl chlorides and amines

Published:2020 Issue:17 Volume:7 Page:2499-2504
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Chen Zhengkai¹²³⁴^ORCID,Wang Le-Cheng¹²³⁴,Zhang Jiajun¹²³⁴,Wu Xiao-Feng¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. Zhejiang Sci-Tech University

3. Hangzhou 310018

4. People's Republic of China

5. Leibniz-Institut für Katalyse e. V. an der Universität Rostock

Abstract

An efficient and practical approach for the synthesis of 2-(trifluoromethyl)quinazolin-4(3H)-ones through palladium-catalyzed three-component carbonylative reaction has been developed.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Zhejiang Sci-Tech University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/QO/D0QO00819B

Reference36 articles.

1. Oxidative Carbonylation as a Powerful Tool for the Direct Synthesis of Carbonylated Heterocycles