Recent advances in transition metal-catalyzed heteroannulative difunctionalization of alkenes via C–H activation for the synthesis of heterocycles

Author:

Liu Jianchao1ORCID,Xiao Xiao1,Lai Yinlong2,Zhang Zhenming3

Affiliation:

1. National Research Centre for Carbohydrate Synthesis, Jiangxi Normal University, Nanchang 330022, P. R. China

2. College of Chemistry and Civil Engineering, Shaoguan University, Shaoguan 512005, Guangdong Province, P. R. China

3. Key Laboratory of Chemical Biology, College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, Jiangxi 330022, P.R. China

Abstract

In this review article, we summarized recent advances in the transition metal-catalyzed heteroannulative difunctionalization of alkenes via direct C–H activation to access heterocyclic frameworks.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangxi Province

Basic and Applied Basic Research Foundation of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Reference144 articles.

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2. J. A.Joule and K.Mills , Heterocyclic Chemistry , Blackwell Science , Oxford , 2000

3. L. D.Quin and J. A.Tyrell , Fundamentals of Heterocyclic Chemistry: Importance in Nature and in the Synthesis of Pharmaceuticals , Wiley , Hoboken, NJ , 2010

4. Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

5. Coumarin heterocyclic derivatives: chemical synthesis and biological activity

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