Excitation ratiometric chloride sensing in a standalone yellow fluorescent protein is powered by the interplay between proton transfer and conformational reorganization-Reference-Cited by-同舟云学术

Excitation ratiometric chloride sensing in a standalone yellow fluorescent protein is powered by the interplay between proton transfer and conformational reorganization

Published:2021 Issue:34 Volume:12 Page:11382-11393
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Chen Cheng¹^ORCID,Tutol Jasmine N.²^ORCID,Tang Longteng¹^ORCID,Zhu Liangdong¹^ORCID,Ong Whitney S. Y.²^ORCID,Dodani Sheel C.²^ORCID,Fang Chong¹^ORCID

Affiliation:

1. Department of Chemistry, Oregon State University, 153 Gilbert Hall, Corvallis, OR 97331-4003, USA

2. Department of Chemistry and Biochemistry, The University of Texas at Dallas, 800 West Campbell Road, Richardson, TX 75080, USA

Abstract

We discovered an interplay between proton transfer and conformational reorganization that powers a standalone fluorescent-protein-based excitation-ratiometric biosensor for chloride imaging.

Funder

Division of Chemistry

National Institute of General Medical Sciences

Division of Molecular and Cellular Biosciences

Welch Foundation

Oregon State University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC00847A