Stereochemistry, lipid length and branching influences Mincle agonist activity of monoacylglycerides-Reference-Cited by-同舟云学术

Stereochemistry, lipid length and branching influences Mincle agonist activity of monoacylglycerides

Published:2020 Issue:3 Volume:18 Page:425-430
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Khan Ayesha¹²³⁴⁵,Braganza Chriselle D.¹²³⁴⁵,Kodar Kristel¹²³⁴⁵,Timmer Mattie S. M.¹²³⁴⁵^ORCID,Stocker Bridget L.¹²³⁴⁵

Affiliation:

1. School of Chemical and Physical Sciences

2. Victoria University of Wellington

3. Wellington

4. New Zealand

5. Centre for Biodiscovery

Abstract

Structure activity relationship of Monoacylglycerides shows enhanced Mincle agonist activity of ligands withsn-1 stereochemistry and long-lipid chains through IL-8 production in human peripheral blood monocytes.

Funder

Marsden Fund

Health Research Council of New Zealand

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/C9OB02302J

Reference38 articles.

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